Intraepithelial carcinoma (Bowen disease)
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U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
U rezultatima Stiftung Warentest-a za 2022. iz Njemačke, zadovoljstvo potrošača ModelDerm-om bilo je samo nešto niže nego s plaćenim telemedicinskim konsultacijama.
Tipičan slučaj – Intraepithelial carcinoma (Bowen disease) može biti pogrešno dijagnostikovan kao dugotrajni ekcem koji ne svrbi.
relevance score : -100.0%
ReferencesBowen's disease (BD) je vrsta raka kože koja počinje u vanjskom sloju kože (epidermu). Češći je kod bijelaca i često se javlja u područjima izloženim sunčevoj svjetlosti, ali se može pojaviti i drugdje. BD se obično pojavljuje kao jedna lezija. BD se često smatra znakom upozorenja prije nego što se razvije ozbiljniji tip raka kože. Da bi dijagnosticirali BD, doktori se obično oslanjaju na ispitivanje uzoraka tkiva pod mikroskopom (biopsija).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowenova bolest (Bowen's disease) uglavnom pogađa bijele osobe starije od 60 godina. Ključni faktori rizika uključuju dugotrajno izlaganje suncu, oslabljen imuni sistem, izloženost arsenu i HPV infekciju kože. HPV sojevi 16, 18, 34 i 48 povezani su s Bowenovom bolešću u genitalnom području. Učešće HPV‑a u ne‑genitalnim slučajevima je manje jasno.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Obično se pojavljuje kao eritematozno, ljuskavo ili ljuštasto područje bilo gdje na tijelu. Najčešća lokacija su potkoljenice.
Izlječiva se različitim metodama, poput krioterapije, kiretaže, kauterizacije, fotodinamičke terapije ili ekscizije lezije.
○ Dijagnoza i liječenje
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy